Accessing Disease-Modifying Therapies for Multiple Sclerosis: A Pan-Canadian Analysis

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Accessing Disease-Modifying Therapies for Multiple Sclerosis: A Pan-Canadian Analysis

Health

Author: Isabelle Gagnon-Arpin, Junyi Feng, Monika Slovinec D’Angelo, Nicholas Moroz

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  • Disease-modifying therapies (DMTs) can reduce the frequency and severity of relapses and slow the progression of disability and new brain lesions in multiple sclerosis (MS) patients.
  • DMTs’ use changed significantly over the past decade, thanks to new, higher-efficacy drugs.
  • DMT claims grew by half between 2010–18. Reimbursement costs also rose, from $386.9 million in 2010 to $607 million in 2018.
  • Over half of DMTs are claimed through private drug plans. Seven per cent are paid for out-of-pocket. In 2018, this represented $39.3 million in spending for individuals and their families.
  • Families affected by MS face a greater financial burden than the average Canadian household. And out-of-pocket costs vary by treatment, province, and drug coverage.
  • Public access to new, innovative DMTs lags behind private drug coverage access.
  • Timely, affordable, and equitable access to DMTs will lead to better outcomes. Health systems and society at large also stand to gain.
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Disease-modifying therapies (DMTs) slow down brain lesions and ease relapses in multiple sclerosis patients—but why can’t Canadians easily access them? This primer examines DMTs’ costs, barriers, policies, and opportunities.

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